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Games
In the Guilty Gear series of fighting games, a character
called A.B.A. is referred to as a homunculus by another
character called Order Sol. A.B.A. is an artificial
being created via science; she is human-like in
appearance and is abnormally tall for a homunculus. She
wields a key-shaped axe weapon called Paracelsus, after
the alchemist who first used the term 'homunculus'.

In the game Descent 3 on level 6 (Noctis Labryinthis),
the player must battle the Homunculus, a boss robot
constructed from scrap metal by the nomads of the
planet.
In the Game Boy Advance video game Fire Emblem: Rekka no
Ken, the main villain Nergal uses henchmen of humanlike
appearance but inhuman disposition and talent created by
means of forbidden magic called morphs, whose means of
creation resemble that of Homunculi.
Homunculus - Imps and minor demons
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